A total of 814 patients with HBeAg-positive chronic hepatitis B received either peginterferon alfa – 2a (180 ?g once weekly) plus oral placebo, peginterferon alfa – 2a .
Background: Hepatitis B virus (HBV) RNA is a novel serum biomarker that has the potential to predict treatment response in patients with chronic hepatitis B . We explored whether HBV RNA serum levels can predict hepatitis B e antigen (HBeAg) seroconversion in patients treated with peginterferon alfa – 2a .
Children with immune-tolerant features of chronic hepatitis B (CHB) received entecavir once-daily in a dose of 0.015 mg/kg (0.5 mg maximum) for 48 weeks peginterferon alfa – 2a (180 µg/1.73m 2 subcutaneously) once-weekly was added at the end of week 8 and continued until week 48. The primary endpoint was lack of detectable hepatitis B e antigen …
The PEG- B -ACTIVE (NCT01519960) phase III study evaluated peginterferon (PegIFN) alfa – 2a treatment in children aged 3 to hepatitis B e antigen (HBeAg)-positive immune-active patients without advanced fibrosis (AF)/cirrhosis were randomized (2:1) to PegIFN alfa – 2a (Group A, n = 101) or no treatment (Group B , n …
What is the Difference Between Peginterferon Alfa 2A and …
Peginterferon Alfa- 2a Injection: MedlinePlus Drug Information, 4/30/2010 · Pharmaceutical Services Division requested an updated systematic review of peginterferon alfa-2a (Pegasys) for the treatment of chronic hepatitis B , previously reviewed by the Therapeutics Initiative in November 2006. Drug. Peginterferon alfa – 2a injection (Pegasys) is categorized as an anti-viral compound and as a biological response modifier.
Keywords: Peginterferon alfa-2a, Hepatitis B virus, Chronic hepatitis B , Genotype, Hepatitis B surface antigen Background Hepatitis B virus (HBV) infection is a common disease that can induce chronic carrier state and is associated with risk of development of progressive disease and he-patocellular carcinoma [1]. Interferon (IFN) and several, 2/28/2020 · Similarities Between Peginterferon Alfa 2A and 2B . Peginterferon – alfa – 2a and 2b are the two types of pegylated interferons widely available for the treatment of chronic hepatitis C (HCV) infection. They are the modified forms of interferon, a drug that mimics a protein in the body that the immune system uses to destroy viruses. They contain a covalently attached …
